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Microbial Fermentation Solutions
Home > Technology > Bioreactor > Microbial Fermentation Solutions > DuoBioX? Explore Multi-Parallel Benchtop Glass Fermenter

DuoBioX? Explore Multi-Parallel Benchtop Glass Fermenter

DuoBioX? Explore is a state-of-the-art microbial fermentation system that boasts industry-leading design, exceptional performance, comprehensive functionality, and user-friendly operation. Users can control one to eight glass tanks with a single computer, allowing them to operate independently or in parallel, significantly accelerating the progress of process development. The DuoBioX? Explore system is ideal for the development and research of fermentation processes within the biopharmaceutical industry.

 

DuoBioX? Explore Multi-Parallel Benchtop Glass FermenterDesign Concept

The DuoBioX? Explore system fully satisfies the technical performance requirements for microbial fermentation tanks in the biopharmaceutical industry. Its process software employs a user-friendly design language, simplifying operation. The controller features a complete set of electrical components from top-tier brands, which are highly integrated to minimize space usage, thus preserving valuable laboratory benchtop areas.

 

DuoBioX? Explore Multi-Parallel Benchtop Glass FermenterMaterial of Construction

The liquid-contact parts of the tank are constructed from SS 316L stainless steel, which has been electrolytically polished and treated with an inert surface for easy cleaning. The glass tank body is made of high-quality tempered borosilicate glass, while the sealing materials consist of EPDM, silicone, and other materials that comply with FDA requirements. The non-liquid contact parts are made from high-quality SS 304 stainless steel.

 

DuoBioX? Explore Multi-Parallel Benchtop Glass FermenterSystem hardware

Adopt a full set of well-known brand hardware to ensure stable and reliable equipment performance:

?  SIEMENS S-1200 PLC

?  Panasonic servo motor

?  METTLER TOLEDO pH gel electrode

?  SMC solenoid valve

?  HAMILTON DO optical electrode

?  Dwyer rotor flow meter

?  Prefluid variable speed peristaltic pump(Watson-Marlow as optional)

?  ALICAT mass flow meter

 

DuoBioX? Explore Multi-Parallel Benchtop Glass Fermenter


DuoBioX? Explore Multi-Parallel Benchtop Glass Fermenter Benefits

?  Multiple tank volume specifications to choose from, including 3 L, 5 L, 7 L, and 15 L.

?  The satellite chassis design provides great flexibility for system expansion and allows rapid multi-link or parallel control of 1 to 8 tanks. The Explore system can easily realize parameter setting, process program call, and data backup between different tanks, and can compare and analyze trends of different batches on the same interface.

?  Powerful software functions can achieve all-round control based on feedback, time, conditions and script recipes, meeting users' stringent process requirements.

?  The operating system developed based on Wincc industrial-grade architecture complies with GMP and 21 CFR Part 11 requirements and can be used in industries such as pharmaceuticals and medical care.

?  Perfect network communication interface, can be connected to SCADA to achieve data acquisition and remote monitoring. The controller reserves additional analog input interfaces to integrate sensors such as CO2/ weight/biomass and to involve external sensors in the control feedback. The system can be expanded to add exhaust gas analysis and online biochemical analysis functions.

?  The system provides a variety of DoE method options, covering screening and optimization functions; the system software is embedded, and the experimental design can be assigned to the satellite tank seamlessly with one click; the result analysis is visualized and graphically output to determine the optimal range.


 

Model

Explore 3L-F

Explore 5L-F

Explore 7L-F

Explore 15L-F

Function

Microbial fermentation, controlling up to 8 tanks

Tank (with baffle)

Nominal volume

3 L

5 L

7 L

15 L

Max working volume

2.2 L

3.6 L

5.0 L

10.8 L

Min working volume

600 mL

1.2 L

1.7 L

3.6 L

Height-to-diameter ratio  (H:D)

2:1

1.8:1

2.2:1

2.:1

Impeller number

2

3

Impeller type

6 straight blades x2

6 straight blades for middle and lower impeller x2, 6 45° inclined blade for upper impeller x1

Blade diameter

65 mm

72 mm

72 mm

86 mm

Sparger tube diameter

4 mm

6 mm

8 mm

8 mm

Bottom sparger diameter

0.8   mm

Number of sparger holes

8

8

8

16

Bottom sparger shape

Ring sparger

Controller

pH electrode

Inpro3100i/SG/   225

EasyFerm Bio PHI Arc 225

Inpro3100i/SG/   325

EasyFerm Bio PHI Arc 325

DO electrode

243666-142/225 (Optical) H2

243666-142/325 (Optical) H2

External interface reserved

1*4-20mA analog input (2 as optional)

Overlay air supply

Air-rotor flowmeter

MFC-Air

0~1 L

0~4 L

0~10 L

0~20 L

MFC-O2

0~1 L

0~4 L

0~10 L

0~20 L

MFC-CO2

Optional

MFC-N2

Optional

Liquid level electrode

Standard

Peristaltic pump

4 x Prefluid KZ12 variable speed peristaltic pump (Waston Malow 114D as optional )

Temp. control

Pt100 temperature electrode; electric blanket 100w; PID control cold water valve adjustment

Exhaust condensation

Cooling water circulation

Load cell

Optional

Control software

21 CFR Part 11

Yes

Data log

Yes

User authorization management

4 levels

Utility requirement

Air source

Air、O2、CO2、N2

Air source pressure

0.2-0.3 MPa

Voltage

220v 50 Hz

Socket

10A three-hole

Control cabinet dimension

Length*Width*Height   554*188*404 mm

Tank external dimensions

Height * Diameter (External) 431*200 mm

Height * Diameter (External) 480*250 mm

Height * Diameter (External) 550*250 mm

Height * Diameter (External) 662*340 mm

I/O cabinet weight

45 kg

Tank net weight

8 kg

10 kg

12 kg

15 kg



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  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
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