久久久精品欧美一区二区三区,国产欧美久久久精品影院,亚洲AV福利天堂一区二区三亚洲欧洲日韩国产AⅤ在线,亚洲成av人在线视,四虎国产精品永久地址99自拍三区一级国产片,亚洲男人的天堂久久无在线观看免费黄视频,亚洲一级特黄大片在线播放,国产成人精品区在线观看

Affinity Chromatography Resin
Home > Technology > Chromatography Resin > Affinity Chromatography Resin > Antibody Purification Resin

Antibody Purification Resin


Affinity chromatography resins are mainly used for the capture and purification of monoclonal antibodies/bispecific antibodies, fusion proteins or other protein molecules with specific binding sites. Considering different purification requirements, Bogen (A Duoning company) provides affinity chromatography media based on polymer hard gel matrix (three series of HP/CP/GP according to pore size) and agarose soft gel matrix.

 

The hard gel chromatography resin developed by Bogen uses high-strength hydrophilic polyacrylate beads as matrix, and adopts unique flexible hydrophilic modification technology to further reduce non-specific adsorption caused by hydrophobic micro surface of hard gel chromatography resins , which helps to improve protein recovery and robustness of purification process.

 

Bogen has developed industry-leading multi-scale micro-nano structure control technology, which can realize the precise regulation of the pore size of the chromatography resin. Based on the size of protein molecular weight, we can provide chromatography resins with different pore sizes:

 

?   HP series affinity chromatography resins: suitable for molecules with MW <200 KD

?   CP series affinity chromatography resins: suitable for molecules with MW 100 KD-300 KD

?   GP series affinity chromatography resins: suitable for molecules or viruses/vaccines with MW > 150 KD

 

Antibody Purification Resin

 

Antibody Purification Resin (GP-ProA) is alkali-resistant affinity chromatography resin developed for purification of monoclonal antibody/bispecific antibody, separating antibody of interest from the impurities through the specific binding between ProA ligand and antibody. This product uses super-macro-porous polyacrylate beads as matrix and alkali-resistant recombinant ProA as binding ligand, featuring high flow rate, low back pressure, and high stability, which are obvious advantages in commercial manufacturing of antibody-based biopharmaceuticals.

 

Antibody Purification Resin (ProG) is affinity chromatography resin specially developed for purification of antibodies from ascites and serum. This product uses agarose-based soft gel beads as matrix and r-ProG as binding ligand, achieving high binding capacity and long-life cycle.

 

Product Features

Product

Antibody purification resin (GP-ProA)

Antibody Purification resin (ProG)

Matrix

Super macroporous polyacrylate hard gel

Agarose soft gel

Ligand

r-Protein A

r-Protein G

Average particle size

70μm

90μm

Ligand density

10mg/mL

5mg/mL

Dynamic capacity

≥40mg/mL

≥30mg/mL

Max flowrate

1500 cm/h

600 cm/h

Max Pressure

1 Mpa

0.3 Mpa

Storage

2-8°C (20% ethanol)

2-8 (20% ethanol)

Applicable range

Monoclonal/bispecific antibodies, Fc fusion protein

Human, mouse, bovine, horse derived IgG

PH Stability

Can withstand 0.5M NaOH cleaning (It is recommended that the cleaning time should not exceed 20 minutes)

3-12 (long term)

2-13 (short term)

 

Case Study

 

Chromogram of mAb purification process by GP-ProA

Antibody Purification Resin

Column size: 0.78cm ID x 10cm

Flowrate: 1 mL/min

Detection wavelength: 280nm

Sample: Clarified mAb cell culture medium

Elution purity: 96.65%

Elution recover rate: 92.51%

Concentration factor: 4-10 x


Ordering Information

 

GP series

Product Name

Part No.

Specification

Product Name

Part No.

Specification

Antibody purification resin (GP-ProG)

BG16-3110-02

50mL

Antibody purification resin (GP-ProA)

BG18-3110-02

50mL

BG16-3110-04

500mL

BG18-3110-04

500mL

BG16-3110-05

1L

BG18-3110-05

1L

BG16-3110-07

10L

BG18-3110-07

10L

BG16-3110-08

20L

BG18-3110-08

20L

 

Agarose series

Product Name

Part No.

Specification

Product Name

Part No.

Specification

Antibody purification resin (ProG)

BG16-0010-02

50mL

Antibody purification resin (ProA)

BG18-0010-02

50mL

BG16-0010-04

500mL

BG18-0010-04

500mL

BG16-0010-05

1L

BG18-0010-05

1L

BG16-0010-07

10L

BG18-0010-07

10L

BG16-0010-08

20L

BG18-0010-08

20L

 

Prepacked column

Product Name

Specification

Applicable   Molecular Weight

Capacity

Max Pressure

Max Flow rate

Application/Feature

Antibody purification column (ProG)

5mL

10mL

≤200KD

30mg/mL

0.3MPa

600cm/h

Used to purify antibodies from ascites and serum

Antibody purification column (GP-ProA)

5mL

10mL

≥150KD

40mg/mL

1MPa

1000cm/h

Used for scale-up study of antibody purification process, high flow rate, low back pressure, high stability

 

 


Relevant Documents

Contact Us
  • Tel.: +86 021 6434 0155
  • E-Mail: marketing@duoningbio.com
  • Address: Building 30, No. 1525 Minqiang Road, Songjiang District, Shanghai
Message

Copyright ? Shanghai Duoning Biotechnology Co., Ltd. All Rights Reserved Sitemap | Technical Support: Reanod

WeChat
WeChat

Message-

Duoning Biotechnology

+86 021 6434 0155

2021精品国产品免费观看| 国产日韩无码一区二区三区久久区| 午夜成人理论无码电影在线播放| 亚亚洲国产精品va在线观看香蕉| 国产真实愉拍系列在线视频| 人与禽性视频77777| 人妻无码不卡中文字幕系列| 国产精品无码A∨精品影院| 欧美中日韩狂热高清视频| 欧美成人午夜一区二区三区| 久久精品国产精品亚洲下载| 久久av片免费一区二区三区| 狠狠88综合久久久久综合网| 国产精品无码不卡免费视频| 亚洲鲁丝片AV无码多人 | 国产91精品对白在线播放| 伊人久久大香线蕉亚洲| 久久久久久久综合日本| 一区香蕉视频亚洲毛片免费一级| 99久久国产综合精麻豆| 欧洲精品久久久av无码电影| 婷婷伊人在线播放国产麻豆| 免费欧洲毛片A级视频无风险| 久精品国产欧美亚洲色aⅴ大片| 精品丰满人妻无套内射| 国产日韩欧美丝袜首页| 暴力调教一区二区三区| 精品国产三级大全在线观看| AV狼友无码国产在线观看不卡| 中文无码乱人伦中文视频播放| 国产一区二区精品在线| 日本国产理论片午午伦夜理片| 97se亚洲国产综合自在线尤物| 人妻换人妻AA视频麻豆| 亚洲精品美女久久久久网站| 欧美一区二区三区爽大粗| 欧美大黑帍在线播放| 成年免费视频黄网站在线观看| 日韩精品无码熟人妻我不卡| 久久国产热这里只有精品| 少妇高潮喷水久久久久久久久久|